The Claim
Gallbladder muscle tissue from individuals with cholesterol gallstones exhibits an elevated cholesterol-to-phospholipid mole ratio in cell membranes, reduced membrane fluidity, and impaired contractile function, suggesting a direct link between membrane lipid composition and gallbladder motility dysfunction.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
People with gallstones made of cholesterol have stiffer cell membranes in their gallbladder muscles, which might make the gallbladder less able to squeeze and empty properly.
See the scientific wording
Gallbladder muscle tissue from individuals with cholesterol gallstones exhibits an elevated cholesterol-to-phospholipid mole ratio in cell membranes, reduced membrane fluidity, and impaired contractile function, suggesting a direct link between membrane lipid composition and gallbladder motility dysfunction.
What the research says
1 studyStudy: Excess membrane cholesterol alters human gallbladder muscle contractility and membrane fluidity.
When people have gallstones made of cholesterol, their gallbladder muscle membranes get too fatty, making them stiff and less able to squeeze properly. When scientists removed the extra cholesterol, the muscle worked better again.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.