The Claim
In individuals with chronic fatigue syndrome, the presence of autoantibodies to selenoprotein P is associated with significantly reduced deiodinase activity (SPINA-GD index), free T3 to free T4 ratios, and total T3 to total T4 ratios compared to individuals without these autoantibodies.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
People with chronic fatigue syndrome who have autoantibodies targeting selenoprotein P show lower levels of markers indicating thyroid hormone conversion to its active form, compared to those without these autoantibodies.
See the scientific wording
Among individuals with chronic fatigue syndrome, those positive for autoantibodies to selenoprotein P have significantly lower deiodinase activity (SPINA-GD index), free T3 to free T4 ratios, and total T3 to total T4 ratios compared to those without these autoantibodies, suggesting impaired conversion of thyroid hormone to its active form.
What the research says
1 studySome people with chronic fatigue syndrome have antibodies that block selenium from reaching the thyroid, which stops the body from turning inactive thyroid hormone into the active form. This study found those people indeed have much lower levels of active thyroid hormone.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.