People with long-term kidney problems tend to have higher levels of certain body chemicals that cause inflammation, and the worse their kidney function gets, the more these chemicals rise — this might be why their kidneys and heart keep getting damaged over time.

This study shows that people with kidney disease often have higher levels of body chemicals that cause inflammation, and those higher levels are linked to their kidneys getting worse and heart problems developing. It confirms that ongoing inflammation is a big reason why kidney disease gets worse.