Among adults with Hashimoto's thyroiditis who have normal selenium levels, taking selenium supplements is linked to a 169% higher relative risk of developing psoriasis over five years.

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Pro

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Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

59

Clinical Outcomes of Selenium Supplementation in Hashimoto's Thyroiditis Without Selenium Deficiency: A Large‐Scale Retrospective Cohort Study

Cohort Study

Human

2026 May

This study found that adults with Hashimoto’s who took selenium supplements were more than twice as likely to develop psoriasis over five years compared to those who didn’t, suggesting selenium might trigger skin-related autoimmune problems even in people who aren’t deficient.

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Source Study

Clinical Outcomes of Selenium Supplementation in Hashimoto's Thyroiditis Without Selenium Deficiency: A Large‐Scale Retrospective Cohort Study

Score: 59

DOI: 10.1002/edm2.70239

Similar Assertions

Among adults with Hashimoto's thyroiditis who have normal selenium levels, taking selenium supplements has been linked to a higher chance of developing other autoimmune conditions, including Sjögren's syndrome, over five years.

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89%

In people with Hashimoto’s thyroiditis, taking selenium supplements raises levels of selenium and certain antioxidant proteins in the blood, and these changes are linked to lower levels of thyroid autoantibodies and TSH.

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86%

In people with Hashimoto's thyroiditis, lower levels of selenium in the blood are linked to higher levels of antibodies that attack the thyroid gland, even when overall selenium levels are not deficient compared to healthy individuals.

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85%

In people with Hashimoto's thyroiditis who have normal selenium levels, taking selenium supplements daily for six months or longer is linked to sustained increases in thyroid antibodies and hormone levels over five years.

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85%

Among adults with Hashimoto's thyroiditis who have normal selenium levels, taking selenium supplements may be linked to a 63% higher chance of dying from any cause over five years, even though there is no evidence it increases the risk of thyroid cancer or the need for thyroid surgery.

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83%