The Claim

Each 100 pmol/L increase in serum vitamin B12 concentration is associated with a 4% higher risk of all-cause mortality in the general population and a 6% higher risk in older adults, suggesting that elevated vitamin B12 levels may serve as a marker of increased mortality risk.

Source: The origin of vitamin B12 levels and risk of all-cause, cardiovascular and cancer specific mortality: A systematic review and dose-response meta-analysis.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
48score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

People with higher levels of vitamin B12 in their blood tend to have a slightly higher chance of dying from any cause — especially older adults — so high B12 might just be a sign that something else is wrong in the body.

See the scientific wording

Each 100 pmol/L increase in serum vitamin B12 concentration is associated with a 4% higher risk of all-cause mortality in the general population and a 6% higher risk in older adults, suggesting elevated vitamin B12 levels may be a marker of increased mortality risk.

What the research says

1 study
  1. Study: The origin of vitamin B12 levels and risk of all-cause, cardiovascular and cancer specific mortality: A systematic review and dose-response meta-analysis.

    This study found that people with higher levels of vitamin B12 in their blood were more likely to die from any cause, especially older adults — just like the claim says. It doesn’t say B12 causes death, but that high levels might signal other health problems.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.