descriptive
Analysis v1
Strong Support
People with systemic lupus erythematosus (SLE) have higher levels of antibodies targeting a specific viral-like protein fragment compared to healthy individuals and people with other autoimmune diseases.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Autoantibodies to human endogenous retrovirus‐K are frequently detected in health and disease and react with multiple epitopes
Cross-Sectional Study
Human
2002 AprScientists found that people with lupus have much higher levels of certain antibodies that stick to a specific part of an ancient virus in our DNA, compared to healthy people or those with other autoimmune diseases. This supports the idea that lupus is linked to a stronger immune reaction to this particular viral fragment.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.