People with metabolic syndrome who follow intermittent fasting see a small drop in their HDL (good) cholesterol, which might not be ideal for heart health.
Scientific Claim
Intermittent fasting reduces HDL cholesterol by 0.06 mmol/L in adults with metabolic syndrome over interventions averaging 3 months, indicating a small but statistically significant decline in 'good' cholesterol.
Original Statement
“HDL level decreased by 0.06 mmol/L (95% CIs: −0.09; −0.02)”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The effect is statistically significant and derived from RCTs. The claim accurately reports the direction and magnitude of the effect without overstatement.
Evidence from Studies
Supporting (0)
Contradicting (1)
Unknown Title
The study looked at how intermittent fasting affects cholesterol and blood sugar, but it didn’t measure 'good' cholesterol (HDL) at all — so we can’t say if it goes up, down, or stays the same.