The Claim

In older mobility-limited adults, serum 25-hydroxyvitamin D concentration is positively associated with skeletal muscle vitamin D receptor protein levels, with a correlation coefficient of 0.67 (P=0.0028), indicating that higher circulating vitamin D levels correspond to greater VDR protein expression in muscle tissue.

Source: Effects of 1,25-Dihydroxyvitamin D3 and Vitamin D3 on the Expression of the Vitamin D Receptor in Human Skeletal Muscle Cells

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
54score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In older adults who have trouble moving around, higher levels of vitamin D in the blood are linked to more vitamin D receptors in their muscles — meaning the more vitamin D they have, the more of these muscle sensors they seem to have.

See the scientific wording

In older mobility-limited adults, serum 25-hydroxyvitamin D concentration is positively associated with skeletal muscle vitamin D receptor protein levels, with a correlation coefficient of 0.67 (P=0.0028), indicating that higher circulating vitamin D levels correspond to greater VDR protein expression in muscle tissue.

What the research says

1 study
  1. Study: Effects of 1,25-Dihydroxyvitamin D3 and Vitamin D3 on the Expression of the Vitamin D Receptor in Human Skeletal Muscle Cells

    The study found that older adults with higher levels of vitamin D in their blood also had more vitamin D receptors in their muscles, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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