When people are obese, their fat tissue doesn’t make enough of a special protein that helps turn omega-3s from fish oil into anti-inflammatory messengers—so the omega-3s don’t work as well to reduce inflammation.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Modification of subcutaneous white adipose tissue inflammation by omega-3 fatty acids is limited in human obesity-a double blind, randomised clinical trial

Randomized Controlled Trial

Human

2022 Mar

In obese people, the body doesn’t activate omega-3 fats (like DHA) as well as in lean people, so they don’t get as much of the anti-inflammatory benefits — and this study shows why.

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Source Study

Modification of subcutaneous white adipose tissue inflammation by omega-3 fatty acids is limited in human obesity-a double blind, randomised clinical trial

Score: 63

DOI: 10.1016/j.ebiom.2022.103909

Similar Assertions

Taking a daily omega-3 supplement for 3 months can calm down the immune system in your fat tissue, even if you're at a normal weight—like turning down the volume on inflammation signals that don't need to be so loud.

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