Taking a daily omega-3 supplement for 3 months can calm down the immune system in your fat tissue, even if you're at a normal weight—like turning down the volume on inflammation signals that don't...

Taking a high dose of omega-3 fish oil every day for three months doesn't make obese women lose weight or change their muscle or fat levels — but their metabolism and inflammation might still get better anyway.

Taking a high dose of fish oil daily for three months may help shift the balance of fats in the body of obese women toward less inflammation, but if they stop taking it, that benefit goes away within a month.

Taking 4 grams of omega-3 supplements daily for 52 days raises the omega-3 levels in red blood cells of healthy young men, indicating that EPA and DHA are incorporated into tissues, but does not lower markers of systemic inflammation following exercise-induced muscle damage.

When people are obese, their fat tissue doesn’t make enough of a special protein that helps turn omega-3s from fish oil into anti-inflammatory messengers—so the omega-3s don’t work as well to reduce inflammation.

Taking fish oil supplements (which have EPA and DHA) might help calm down skin inflammation by boosting natural healing chemicals and lowering inflammation signs, but sometimes it works really well and other times it doesn’t — it’s inconsistent.