correlational
Analysis v1
Strong Support
People with rare harmful changes in the BRCA1 or BRCA2 genes tend to live shorter lives, mostly because they’re more likely to get cancers like breast and ovarian cancer.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Rare genetic associations with human lifespan in UK Biobank are enriched for oncogenic genes
Cohort Study
Human
2025 Feb 28The study found that people with harmful BRCA1 or BRCA2 gene variants tend to live shorter lives, mostly because of higher cancer risk, which supports the main idea of the claim.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.