People with severe obesity have more of both helpful and harmful immune cells floating in their blood than people who are lean, meaning their immune systems are more active in complex ways.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Supplementation with EPA and DHA omega-3 fatty acids improves peripheral immune cell mitochondrial dysfunction and inflammation in subjects with obesity.

Case-Control Study

Human

2023 Oct

The study found that people with severe obesity have more of these immune cells in their blood than lean people, which is exactly what the claim says — even though the study also tested omega-3 supplements, that doesn’t change the baseline finding.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Supplementation with EPA and DHA omega-3 fatty acids improves peripheral immune cell mitochondrial dysfunction and inflammation in subjects with obesity.

Score: 32

DOI: 10.1016/j.jnutbio.2023.109415

Similar Assertions

Taking a daily fish oil supplement with about 5 grams of omega-3s for a month may lower both the good and bad immune cells in the blood of people with severe obesity — but we don’t yet know if this is helpful or just a side effect.

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