Omega-3s help tired immune cells in obese people
Supplementation with EPA and DHA omega-3 fatty acids improves peripheral immune cell mitochondrial dysfunction and inflammation in subjects with obesity.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Both pro-inflammatory AND anti-inflammatory immune cell subsets were reduced after omega-3 supplementation.
Common belief is that omega-3s only reduce harmful inflammation, not beneficial regulatory cells. Reducing Tregs and Bregs could theoretically weaken immune balance.
Practical Takeaways
Consider taking 5.25g daily of combined EPA/DHA (e.g., 3.5g EPA + 1.75g DHA) for one month if you have obesity and chronic inflammation.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Both pro-inflammatory AND anti-inflammatory immune cell subsets were reduced after omega-3 supplementation.
Common belief is that omega-3s only reduce harmful inflammation, not beneficial regulatory cells. Reducing Tregs and Bregs could theoretically weaken immune balance.
Practical Takeaways
Consider taking 5.25g daily of combined EPA/DHA (e.g., 3.5g EPA + 1.75g DHA) for one month if you have obesity and chronic inflammation.
Publication
Journal
The Journal of nutritional biochemistry
Year
2023
Authors
Angélica I. Borja-Magno, J. Furuzawa-Carballeda, M. Guevara-Cruz, C. Arias, J. Granados, H. Bourges, Armando R. Tovar, B. Sears, L. Noriega, F. E. Gomez
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Claims (4)
Eating fish or fish oil rich in EPA and DHA omega-3s may help make dangerous fatty buildups in your arteries more stable and less likely to burst, by calming down harmful inflammation and helping your blood vessels relax better.
Taking a daily fish oil supplement with specific amounts of EPA and DHA for a month may help the energy factories inside certain blood cells work better in people with moderate obesity.
People with severe obesity have more of both helpful and harmful immune cells floating in their blood than people who are lean, meaning their immune systems are more active in complex ways.
Taking a daily fish oil supplement with about 5 grams of omega-3s for a month may lower both the good and bad immune cells in the blood of people with severe obesity — but we don’t yet know if this is helpful or just a side effect.