descriptive
PGC-1alpha helps change muscle fibers to be better at using oxygen for energy production
Scientific Claim
PGC-1alpha promotes muscle tissue remodeling toward a more oxidative metabolic profile
Original Statement
“promotes the remodeling of muscle tissue to a fiber-type composition that is metabolically more oxidative and less glycolytic in nature”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a well-established function of PGC-1alpha that has been demonstrated in multiple studies. The study correctly states this relationship without implying causation beyond what is known.
Evidence from Studies
Supporting (1)
0
0
PGC-1alpha: a key regulator of energy metabolism
Narrative Review
2006 DecContradicting (0)
0
No contradicting evidence found