A long time ago, almost no one got heart attacks, cancer, or diabetes—but now lots of people do.

The introduction of industrial seed oils into the American food supply coincided temporally with the emergence and exponential rise in recorded cases of cardiovascular disease and metabolic disorders.

As Americans started eating more processed vegetable oils, rates of insulin resistance and diabetes went up at almost the same time—this timing suggests the two might be connected.

The historical incidence of acute myocardial infarction in the United States was negligible prior to the widespread introduction of industrial seed oils in the early 20th century.

Prior to the widespread consumption of industrial seed oils and refined carbohydrates in the early 20th century, clinical cases of atherosclerotic cardiovascular disease were exceptionally rare in human populations consuming diets high in animal fats.