The Claim
Mechanical stretching of the stratum corneum by a non-penetrating porous micropost array reduces transdermal electrical resistance to levels comparable to those achieved by sharp microneedles that physically penetrate the skin.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
A non-penetrating array of tiny posts that stretch the outer skin layer lowers electrical resistance through the skin to the same level as sharp microneedles that pierce the skin.
See the scientific wording
Mechanical stretching of the stratum corneum by a non-penetrating porous micropost array reduces transdermal electrical resistance to levels comparable to those achieved by sharp microneedles that physically penetrate the skin, suggesting that physical deformation alone can enhance skin permeability.
When the outer skin layer is stretched by a porous array of blunt posts, the cells and fats between them get pulled apart, creating temporary gaps that let larger molecules pass through. An electric field then pushes these molecules through those gaps, making the skin much more permeable without breaking it.
What the research says
1 studyA special array of blunt, porous posts pressed onto skin can make it just as easy for substances to pass through as sharp needles that poke the skin—without breaking the skin at all. This means stretching the outer skin layer alone can help medicines get through.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.