mechanistic
Analysis v1
Strong Support
When you're under a lot of stress, your body's natural calming system slows down, which lets inflammation run wild—and that inflammation can make you feel even more stressed, creating a cycle.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature
Systematic Review With Meta-Analysis
Human
2018 MarWhen people are stressed for a long time, their body’s natural calming system (the vagus nerve) slows down, which can make inflammation worse — this study shows that stress really does quiet down this calming system.
Contradicting (0)
0
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No contradicting evidence found
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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.