Turning up certain genes in baby mouse wounds stops them from healing perfectly and causes too many nerves to grow back — suggesting these genes can mess up natural repair.

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Evidence from Studies

Supporting (1)

18

Community contributions welcome

18

Hyperinnervation inhibits organ-level regeneration in mammalian skin.

Cohort Study

Animal

2026 Mar 20

The study shows that turning on certain genes in baby mouse wounds stops them from healing fully and causes too many nerves to grow, just like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Hyperinnervation inhibits organ-level regeneration in mammalian skin.

Score: 18

DOI: 10.1016/j.cell.2026.02.027

Similar Assertions

After birth, certain skin cells that show up in wounds—called PWFs—don’t exist in baby or embryo wounds. These cells are linked to worse healing and too much nerve regrowth in mice.

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82%

In baby mice with skin wounds, certain skin cells send out a signal that pulls in nerve fibers, making the wound too sensitive. If we turn off that signal, the nerves don’t overgrow and the skin heals better.

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73%