Putting melatonin on the scalp might help reduce damage from pollution and sun, and could help hair grow better by protecting hair cells.
Evidence from Studies
No evidence studies found yet.
What Would Prove This
Per GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this claim, ordered from strongest to weakest.
Whether topical melatonin can effectively treat hair loss
A double-blind, placebo-controlled RCT of 400 women aged 30–55 with androgenetic alopecia, using 0.1% melatonin solution vs vehicle twice daily for 6 months, measuring change in anagen hair count, hair density, and patient-reported outcomes
The overall efficacy and safety of melatonin for hair loss across all trials
A systematic review and meta-analysis of all RCTs on topical melatonin for alopecia, assessing hair count, density, and adverse events, with subgroup analysis by sex and alopecia type