Racecadotril, a drug used for diarrhea, blocks the DIO2 enzyme more effectively and specifically than any other compound tested in this study, without harming cells, even at high doses, making it...

Evidence from Studies

Supporting (1)

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Novel Deiodinase 2-Selective Inhibitors—Possible Reference Substances for Regulatory In Vitro Tests for Endocrine Disruptors and Drugs Targeting T3-Dependent Processes

Computational/Algorithm Study

In Vitro

2026 Apr

Contradicting (0)

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No contradicting evidence found

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Source Study

Novel Deiodinase 2-Selective Inhibitors—Possible Reference Substances for Regulatory In Vitro Tests for Endocrine Disruptors and Drugs Targeting T3-Dependent Processes

DOI: 10.1177/10507256261425689