About 19% of human cancers have mutations in the RAS gene family, with KRAS being the most common.
Strongly supported
Multiple high-quality studies back this claim.
Not medical advice. For informational purposes only. Always consult a healthcare professional.
About 19% of human cancers have mutations in the RAS gene family, with KRAS being the most common.
See the technical phrasing
Mutations in the RAS gene family, primarily KRAS, are present in approximately 19% of all human cancers.
A change in the KRAS gene causes the protein it makes to stay permanently switched on, forcing cells to keep dividing without stopping, which leads to tumor formation.
What the research says
Supports
3 studies
Study: Prevalence and breakdown of KRAS driver mutations in a large UK non-small cell lung cancer cohort
This study provides evidence supporting the claim.
Contradicts
0 studies
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 3 supporting studies