Reverse T3 is a byproduct of your thyroid hormone system that doesn't activate your body's metabolism like normal thyroid hormones do. Instead, it acts like a traffic cop that redirects your thyroid hormones away from becoming active, helping your body control how much thyroid hormone is actually available to use.

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Evidence from Studies

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Clinical and laboratory aspects of 3,3′,5′-triiodothyronine (reverse T3)

Narrative Review

Human

2021 Jan

The study confirms that reverse T3 is an inactive byproduct of thyroid hormone processing that weakly binds to receptors and helps regulate how much active thyroid hormone the body produces.

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Source Study

Clinical and laboratory aspects of 3,3′,5′-triiodothyronine (reverse T3)

Score: 1

DOI: 10.1177/0004563220969150

Similar Assertions

Reverse T3 is a naturally occurring thyroid hormone byproduct that makes up a significant portion of thyroid hormones in your blood. It's created when your body converts another hormone called T4, and its levels stay steady enough that doctors can easily measure them with current lab tests.

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A substance called rT3 blocks your body's active thyroid hormones from working properly by taking their place on cellular receptors. This prevents your cells from getting the energy signals they need, which ultimately slows down your metabolism.

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A thyroid hormone byproduct called Reverse T3 might attach to receptors outside the cell nucleus and help cells multiply. However, scientists aren't sure yet if this actually matters for human health or could be used to treat diseases involving abnormal cell growth.

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