The Claim

Linkage analysis identified chromosome 12q11 as a genomic region significantly associated with idiopathic short stature and height in families with multiple affected children, and this region overlaps with the location of the vitamin D receptor gene.

Source: Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
29score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Scientists found a specific spot on chromosome 12 that seems to be linked to why some kids are much shorter than average, and this spot is right next to a gene that helps the body use vitamin D.

See the scientific wording

Linkage analysis identified chromosome 12q11 as a region significantly associated with idiopathic short stature and height in families with multiple affected children, overlapping with the location of the vitamin D receptor gene.

What the research says

1 study
  1. Study: Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

    Scientists found that a specific spot on chromosome 12, where the vitamin D receptor gene is located, is linked to kids being shorter than normal, and a change in that gene seems to be part of the reason.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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