Semaglutide might help slow down joint damage in people with metabolic issues, even beyond just helping them lose weight — it could be protecting the joints directly.

Semaglutide might help protect knee cartilage and reduce joint swelling in osteoarthritis, even without people losing weight.

Semaglutide, a medication used for weight management, may help protect joint cartilage and decrease inflammation in osteoarthritis even when it does not cause weight loss.

Semaglutide might protect cartilage and help with osteoarthritis by directly affecting cartilage cells, not just by helping people lose weight.

Semaglutide might protect knee cartilage in arthritis, and it's not just because people lose weight — it seems to work directly on the joint, even when diet is kept the same.

A diabetes drug called semaglutide might help protect knee joints in obese mice with arthritis—even if they don’t lose weight.