Taking a weekly semaglutide shot (2.4 mg) for about a year and a half can help lower blood pressure, blood sugar, bad cholesterol, and body-wide inflammation in adults with extra weight but no...

Even if you don’t have diabetes, if you’re overweight and have heart disease, a weekly shot of semaglutide can cut your risk of heart attack or stroke by 1 in 5 — and this benefit starts before you lose much weight.

In adults with obesity taking semaglutide for 12 months, measurable improvements were seen in blood sugar, cholesterol, blood pressure, liver enzymes, and cardiovascular risk indicators.

In obese adults with existing heart disease but no diabetes, a weekly injection of semaglutide at 2.4 mg is associated with a lower rate of serious heart-related events such as heart attack or stroke.

In adults over 45 with heart disease and obesity but no diabetes, a weekly injection of semaglutide at 2.4 mg for about 3.3 years lowers the combined risk of heart-related death, heart attack, or stroke compared to a placebo.

Taking a weekly semaglutide shot (2.4 mg) for about a year helps people with extra weight feel more physically capable and improves their overall quality of life—more than a dummy pill would.