For adults who are overweight, have heart disease, but don’t have diabetes, taking a weekly semaglutide shot might help slow down how fast their kidneys lose function each year.

For adults who are overweight, have heart disease, and early kidney problems but not diabetes, taking a weekly semaglutide shot might help their kidneys work better over two years compared to a placebo.

Taking a weekly semaglutide shot (2.4 mg) for about a year and a half can help lower blood pressure, blood sugar, bad cholesterol, and body-wide inflammation in adults with extra weight but no diabetes—better than a placebo.

Taking a weekly semaglutide shot (2.4 mg) for about a year helps people with extra weight feel more physically capable and improves their overall quality of life—more than a dummy pill would.

A weekly shot called semaglutide helped people with extra weight lose nearly 6 inches off their waist over a year and a half, much more than a fake treatment did — which means it may really help reduce belly fat and lower heart and metabolic disease risks.

The kidney benefits from taking a weekly semaglutide shot for weight and heart health probably aren't just because it lowers blood sugar or blood pressure — there might be other ways it's helping the kidneys.