The difference in sodium and potassium ion concentrations across nerve cell membranes sets the baseline level of nerve activity, and magnesium reduces the likelihood of nerve cells firing too much.
Strongly supported
Multiple high-quality studies back this claim.
Not medical advice. For informational purposes only. Always consult a healthcare professional.
The difference in sodium and potassium ion concentrations across nerve cell membranes sets the baseline level of nerve activity, and magnesium reduces the likelihood of nerve cells firing too much.
See the technical phrasing
Sodium and potassium gradients determine neuronal baseline excitability, and magnesium inhibits excessive neuronal firing.
The balance of sodium and potassium ions inside and outside nerve cells determines how easily they fire. When sodium builds up outside or potassium builds up inside, the cell becomes more likely to fire. If this balance breaks down, the cell fires too much or randomly. Magnesium sits in the middle of a special channel that lets calcium in when the cell is overstimulated, and it blocks that channel so the cell can't fire too hard.
What the research says
Supports
4 studies
Study: Plasma sodium levels are related to resting motor threshold in healthy humans
This study provides evidence supporting the claim.
Contradicts
0 studies
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 4 supporting studies