correlational
Analysis v1
Strong Support
Some people of African descent have genetic changes in a gene called PCSK9 that seem to cut bad cholesterol levels by almost half—this might help explain why they have lower heart disease risk.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
Cross-Sectional Study
Human
2005 FebThe study found that certain genetic changes (Y142X and C679X) in the PCSK9 gene cause much lower 'bad' cholesterol in people of African descent, just like the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.