Some people in China with high blood pressure have a specific gene change that makes their blood pressure spike even more when they eat a lot of salt.

41

Pro

0

Against

Evidence from Studies

Supporting (1)

41

Community contributions welcome

41

Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading

Cross-Sectional Study

Human

2018 Mar 10

Scientists gave people with high blood pressure a lot of salt and found that those with certain changes in the SLC8A1 gene had bigger spikes in their blood pressure — exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading

Score: 41

DOI: 10.1093/ajh/hpx179

Similar Assertions

Scientists think a specific gene called SLC8A1 might affect how your blood pressure reacts when you eat a lot of salt, at least in people of Han Chinese descent who already have high blood pressure.

41

0

94%

In people of Han Chinese descent with high blood pressure, having a specific version of a gene (rs434082 A) seems to make their blood pressure rise a little more when they eat a lot of salt, even after accounting for how much salt they’ve excreted and their age.

41

0

85%