Some people with certain types of thyroid inflammation (like Hashimoto's or subacute thyroiditis) can have a substance called TDA in their blood, but it doesn't actually turn on the thyroid like it does in Graves’ disease — so TDA might not mean the thyroid is being overstimulated.

32

Pro

0

Against

Evidence from Studies

Supporting (1)

32

Community contributions welcome

32

Correlation between thyrotropin-displacing activity and human thyroid-stimulating activity by immunoglobulins from patients with Graves' disease and other thyroid disorders.

Cross-Sectional Study

Human

1979 Mar

The study shows that some people with certain thyroid diseases (not Graves’ disease) can have a marker called TDA without actual thyroid stimulation, which means TDA alone doesn’t mean the thyroid is being overactivated.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Correlation between thyrotropin-displacing activity and human thyroid-stimulating activity by immunoglobulins from patients with Graves' disease and other thyroid disorders.

Score: 32

DOI: 10.1210/JCEM-48-3-398

Similar Assertions

In people with Graves’ disease, a blood marker called TDA doesn’t seem to predict how much their thyroid is being stimulated — even when they’re not on treatment or when they’re in remission.

32

0

87%

Most people with untreated Graves' disease have certain immune proteins in their blood that can affect the thyroid, but not everyone has them.

32

0

85%

In people with an overactive thyroid caused by Graves’ disease, a certain blood signal called hTSA shows up more often than another one called TDA, which might mean it's a better clue for doctors to spot the disease.

32

0

79%