The Claim
Soy isoflavone supplements containing more than 18.8 mg of genistein per day reduce hot flash frequency by more than twofold compared to supplements with lower genistein content in menopausal women.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Menopausal women who take soy isoflavone supplements with more than 18.8 mg of genistein daily experience more than twice the reduction in hot flashes compared to those taking supplements with less genistein.
See the scientific wording
Soy isoflavone supplements containing more than 18.8 mg of genistein per day are more than twice as effective at reducing hot flash frequency as supplements with lower genistein content, indicating a dose-response relationship in menopausal women.
Genistein binds to a specific receptor in the brain that normally responds to estrogen, which calms down a region that controls body temperature. When this region is less active, the body stops triggering sudden heat waves.
What the research says
1 studyThe study found that soy supplements with more than 18.8 mg of genistein cut hot flashes in half more often than those with less genistein, meaning higher doses really do work better for menopausal women.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.