Statins seem to trigger a cellular cleanup process in the liver that accidentally makes the liver produce more sugar.

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Pro

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Against

Evidence from Studies

Supporting (1)

6

Community contributions welcome

6

Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction

Cohort Study

Animal

2015 Nov 2

This study found that statins, which are cholesterol-lowering drugs, trigger a cellular cleanup process called autophagy in the liver, and that this cleanup process causes the liver to make more sugar, raising blood sugar levels.

Contradicting (0)

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No contradicting evidence found

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Source Study

Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction

Score: 6

DOI: 10.1080/15548627.2015.1091139

Similar Assertions

Taking statins long-term may make the body less responsive to insulin, because the liver keeps making too much sugar thanks to a cellular cleanup process.

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Taking statins for a long time may cause the liver to make more sugar, which can raise blood sugar levels.

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