Stem cell vesicles delivered through the nose improve the function of energy-producing mitochondria and reduce oxidative damage in the brains of aged mice, helping cells maintain healthier metabolism.

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Evidence from Studies

Supporting (1)

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Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Cohort Study

Animal & In Vitro

2026 Feb

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No contradicting evidence found

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Source Study

Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Score: 13

DOI: 10.1002/jev2.70232