Stem cell vesicles delivered through the nose reduce a key inflammatory pathway (cGAS-STING) and its downstream interferon signals in the brains of aged mice, which may help calm chronic brain...

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Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Cohort Study

Animal & In Vitro

2026 Feb

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Intranasal Human NSC‐Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS‐STING Signalling, in Aged Hippocampus

Score: 13

DOI: 10.1002/jev2.70232