The Claim
Sulforaphane is the first identified naturally occurring antagonist of the human steroid and xenobiotic receptor (SXR/hPXR), a nuclear receptor that regulates the expression of drug-metabolizing enzymes.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Sulforaphane is a compound found in nature that directly blocks the human SXR/hPXR receptor, which controls the production of enzymes that break down drugs and toxins.
See the scientific wording
Sulforaphane is the first identified naturally occurring antagonist of the human steroid and xenobiotic receptor (SXR/hPXR), a nuclear receptor that regulates the expression of drug-metabolizing enzymes.
Sulforaphane attaches to a specific receptor in liver cells that normally turns on enzymes to break down drugs. When sulforaphane binds, it blocks the receptor from activating the gene that makes the CYP3A4 enzyme. Without this enzyme, the liver cannot process certain drugs as quickly.
What the research says
1 studySulforaphane, a compound in broccoli, was found to block a human body receptor that normally turns on liver enzymes to process drugs. This is the first time a natural substance has been shown to do this.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.