The Claim
In adults with chronic schizophrenia receiving stable risperidone therapy, daily supplementation with 1 mg of vitamin B12 or 1 mg of folic acid for eight weeks increases serum vitamin B12 concentrations by 177–211 pg/mL and serum folate concentrations by 3.4–3.6 ng/mL.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In adults with chronic schizophrenia taking stable risperidone, taking 1 mg of vitamin B12 or 1 mg of folic acid daily for eight weeks raises blood levels of vitamin B12 by 177–211 pg/mL and folate by 3.4–3.6 ng/mL.
See the scientific wording
In adults with chronic schizophrenia receiving stable risperidone therapy, daily supplementation with 1 mg of vitamin B12 or 1 mg of folic acid for eight weeks significantly increases serum concentrations of the respective vitamins, with mean increases of 177–211 pg/mL for vitamin B12 and 3.4–3.6 ng/mL for folate, confirming biological exposure to the intervention.
When a person takes a vitamin B12 or folic acid pill, the vitamins are absorbed from the gut into the bloodstream, where they bind to carrier proteins and circulate at higher levels, directly raising the amount measured in blood tests.
What the research says
1 studyThe study gave people with long-term schizophrenia daily B12 or folic acid pills for eight weeks and found their blood levels of these vitamins went up a lot — exactly what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.