The Claim
Daily supplementation with 180 µg of menaquinone-7 for one year reduces vascular stiffness in post-menopausal women with elevated dp-ucMGP levels, as evidenced by a 40% lower increase in Young’s modulus compared to placebo (9.38% vs. 49.14%, p=0.044), indicating a direct causal effect on arterial wall elasticity in this subgroup.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking 180 micrograms of menaquinone-7 daily for one year results in a 40% smaller increase in arterial stiffness compared to placebo in post-menopausal women with elevated dp-ucMGP levels.
See the scientific wording
Daily supplementation with 180 µg of menaquinone-7 for one year significantly reduces vascular stiffness in post-menopausal women with elevated dephosphorylated-undercarboxylated matrix Gla protein (dp-ucMGP) levels, as measured by a 40% lower increase in Young’s modulus compared to placebo (9.38% vs. 49.14%, p=0.044), indicating a direct causal effect on arterial wall elasticity in this high-risk subgroup.
Vitamin K2 activates a protein in artery walls that traps calcium and stops it from building up in the elastic layers. When calcium doesn't accumulate, the arteries stay flexible and don't stiffen over time.
What the research says
1 studyIn a study of older women with a specific blood marker of poor vitamin K status, those who took 180 micrograms of vitamin K2 daily for a year had much less stiffening of their arteries than those who took a dummy pill. The difference was clear and statistically significant.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.