In adults with Hashimoto's thyroiditis who are not taking levothyroxine, taking 200 micrograms of selenium yeast daily for six months is linked to a measurable decrease in two types of thyroid antibodies, while those not taking selenium show no change.

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Evidence from Studies

Supporting (1)

56

Community contributions welcome

56

Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial

Randomized Controlled Trial

Human

2021 Jul

This study found that taking selenium supplements for six months lowered harmful antibodies in people with Hashimoto’s thyroiditis, while those who didn’t take supplements saw no change — so selenium appears to help calm the immune system’s attack on the thyroid.

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No contradicting evidence found

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Source Study

Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial

Score: 56

DOI: 10.1111/cts.12993

Similar Assertions

In people with Hashimoto's thyroiditis who have normal selenium levels, taking selenium supplements daily for six months or longer is linked to sustained increases in thyroid antibodies and hormone levels over five years.

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In people with Hashimoto's thyroiditis, lower levels of selenium in the blood are linked to higher levels of antibodies that attack the thyroid gland, even when overall selenium levels are not deficient compared to healthy individuals.

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88%

In people with early-stage Hashimoto’s thyroiditis who are not taking thyroid medication, taking 200 micrograms of selenium yeast daily for six months is linked to a small decrease in TSH hormone levels, whereas those not taking selenium experience a small increase.

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88%

Taking selenium supplements may lower levels of thyroid peroxidase antibodies in adults with chronic autoimmune thyroiditis who are already taking levothyroxine, with the greatest reduction seen at six months. However, it does not change thyroid-stimulating hormone levels or improve symptoms related to the condition.

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In people with autoimmune hypothyroidism taking levothyroxine, taking 200 micrograms of selenium daily for a year may lower levels of thyroid peroxidase antibodies by about 19% compared to a placebo, but it does not change the required dose of thyroid hormone or the balance between free triiodothyronine and free thyroxine.

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