The Claim

In adults with Hashimoto's thyroiditis not receiving levothyroxine, daily supplementation with 200 μg of selenium yeast for six months is associated with a statistically significant reduction in thyroid peroxidase antibodies (TPOAb) by an average of 28.4 IU/mL and thyroglobulin antibodies (TGAb) by 48.8 IU/mL, compared to no change in the control group.

Source: Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
56score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In adults with Hashimoto's thyroiditis who are not taking levothyroxine, taking 200 micrograms of selenium yeast daily for six months is linked to a measurable decrease in two types of thyroid antibodies, while those not taking selenium show no change.

See the scientific wording

In adults with Hashimoto's thyroiditis not receiving levothyroxine, daily supplementation with 200 μg of selenium yeast for six months is associated with a statistically significant reduction in thyroid peroxidase antibodies (TPOAb) by an average of 28.4 IU/mL and thyroglobulin antibodies (TGAb) by 48.8 IU/mL, compared to no change in the control group, suggesting selenium may modulate autoimmune activity in this population.

What the research says

1 study
  1. Study: Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial

    This study found that taking selenium supplements for six months lowered harmful antibodies in people with Hashimoto’s thyroiditis, while those who didn’t take supplements saw no change — so selenium appears to help calm the immune system’s attack on the thyroid.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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