The Claim

Short-term creatine supplementation at a dose of 21 grams per day for 5 days increases total muscle creatine content by approximately 21% in young, healthy men, demonstrating effective uptake of exogenous creatine into human skeletal muscle under these dosing conditions.

Source: No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
30score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

If young, healthy guys take a lot of creatine for 5 days straight, their muscles soak it up and end up with about 21% more creatine inside them.

See the scientific wording

Short-term creatine supplementation (21 g/day for 5 days) increases total muscle creatine content by approximately 21% in young, healthy men, confirming effective uptake of exogenous creatine into human skeletal muscle under these dosing conditions.

What the research says

1 study
  1. Study: No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise.

    The study gave men 21 grams of creatine per day for 5 days and found their muscle creatine levels went up by about 21%, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.