The Claim

Daily supplementation with 375 μg of vitamin MK-7 for three years has no significant effect on the rate of bone mineral density decline at the lumbar spine, femoral neck, or total hip in postmenopausal women with osteopenia, regardless of concurrent calcium and vitamin D intake.

Source: The effect of vitamin MK-7 on bone mineral density and microarchitecture in postmenopausal women with osteopenia, a 3-year randomized, placebo-controlled clinical trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
78score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

Taking 375 micrograms of vitamin MK-7 every day for three years does not change how quickly bone density decreases in the spine, hip, or femoral neck in postmenopausal women with low bone density, even when they also take calcium and vitamin D.

See the scientific wording

Supplementation with 375 μg of vitamin MK-7 daily for three years has no significant effect on the rate of bone mineral density decline at the lumbar spine, femoral neck, or total hip in postmenopausal women with osteopenia when compared to placebo, despite concurrent calcium and vitamin D intake.

Why this might work

Vitamin MK-7 activates a protein-making process in bone cells that helps a bone protein bind to minerals, but this activation does not slow down the natural loss of bone density in postmenopausal women with low bone mass, even when they take calcium and vitamin D.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: The effect of vitamin MK-7 on bone mineral density and microarchitecture in postmenopausal women with osteopenia, a 3-year randomized, placebo-controlled clinical trial

    Taking 375 micrograms of vitamin MK-7 every day for three years didn't help slow down bone loss in the spine or hips of postmenopausal women who were already taking calcium and vitamin D — their bones got just as weak as those who took a placebo.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.