The Claim

Seven days of supplementation with 400 mg caffeine, 5 g creatine nitrate, or their combination has no statistically significant effect on resistance exercise performance or anaerobic power in resistance-trained male athletes, as measured by bench press, leg press, and Wingate test outcomes.

Source: The Effect of Creatine Nitrate and Caffeine Individually or Combined on Exercise Performance and Cognitive Function: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

Taking 400 mg of caffeine, 5 g of creatine nitrate, or both for seven days does not improve strength or short-burst power in trained male athletes, based on measurements from bench press, leg press, and Wingate tests.

See the scientific wording

Seven days of supplementation with 400 mg caffeine, 5 g creatine nitrate, or their combination does not significantly improve resistance exercise performance or anaerobic power in resistance-trained male athletes, as measured by bench press, leg press, and Wingate test outcomes, despite observed mean changes that did not reach statistical significance.

Why this might work

Caffeine blocks a brain chemical that slows down nerve cells, making the brain more active. Creatine nitrate provides extra energy to brain cells and opens blood vessels in the brain, delivering more oxygen and fuel. Together, they make the brain work faster and more efficiently during tasks that require focus and quick thinking.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: The Effect of Creatine Nitrate and Caffeine Individually or Combined on Exercise Performance and Cognitive Function: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial

    The study gave men caffeine and creatine nitrate for a week and checked if they could lift heavier or sprint faster—turns out, they couldn’t. So the supplements didn’t make them stronger or more powerful.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.