The Claim
Oral supplementation with 400 micrograms of vitamin K2 daily for 12 months has no effect on carotid-femoral pulse wave velocity in adults with chronic kidney disease stages 3b or 4.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking 400 micrograms of vitamin K2 daily for one year does not change arterial stiffness in adults with moderate to severe chronic kidney disease.
See the scientific wording
Oral supplementation with 400 micrograms of vitamin K2 daily for 12 months does not improve carotid-femoral pulse wave velocity, a measure of arterial stiffness, in adults with chronic kidney disease stages 3b or 4, indicating that this intervention does not reduce vascular stiffness in this population under these conditions.
Taking vitamin K2 daily does not change the hardening of large arteries because the arteries in people with severe kidney disease are already too damaged for vitamin K2 to reverse the buildup of calcium or fix the elastic fibers.
What the research says
1 studyThis study gave people with kidney disease 400 micrograms of vitamin K2 every day for a year and found their arteries didn’t become less stiff. So, the supplement didn’t help.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.