The Claim
Daily ingestion of 61-64 mg of cafestol for 28 days in healthy adult males increases total serum cholesterol by 0.79 mmol/L (31 mg/dL), LDL cholesterol by 0.57 mmol/L (22 mg/dL), fasting triacylglycerols by 0.65 mmol/L (58 mg/dL), and alanine aminotransferase by 18 U/L, indicating a direct causal effect on lipid metabolism and liver enzyme levels.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Consuming 61-64 milligrams of cafestol daily for 28 days raises total serum cholesterol by 0.79 mmol/L, LDL cholesterol by 0.57 mmol/L, fasting triacylglycerols by 0.65 mmol/L, and alanine aminotransferase by 18 U/L in healthy adult males.
See the scientific wording
Daily ingestion of 61-64 mg of cafestol for 28 days in healthy adult males increases total serum cholesterol by 0.79 mmol/L (31 mg/dL), LDL cholesterol by 0.57 mmol/L (22 mg/dL), fasting triacylglycerols by 0.65 mmol/L (58 mg/dL), and alanine aminotransferase by 18 U/L, indicating a direct causal effect on lipid metabolism and liver enzyme levels.
Cafestol blocks the liver from removing cholesterol from the blood and stops it from turning cholesterol into bile acids, so cholesterol and fats build up in the blood and the liver gets stressed.
What the research says
1 studyThis study gave healthy men 61–64 mg of cafestol every day for four weeks and found their blood cholesterol, triglycerides, and liver enzyme levels went up—exactly what the claim says. So yes, cafestol really does affect these body markers.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.