Taking 83 micrograms of L-selenomethionine daily during pregnancy does not change thyroid hormone levels, thyroid size, or tissue appearance in women with autoimmune thyroiditis. This suggests the supplement affects immune markers related to the thyroid without altering thyroid structure or function.

67

Pro

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Against

Evidence from Studies

Supporting (1)

67

Community contributions welcome

67

Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial

Randomized Controlled Trial

Human

2019 Dec

Taking this specific form of selenium during pregnancy helped lower harmful antibodies in moms with thyroid issues, but didn’t change how their thyroid looked or worked—so it’s helping the immune system, not the thyroid itself.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial

Score: 67

DOI: 10.1007/s12020-019-01958-1

Similar Assertions

Taking 83 micrograms of L-selenomethionine daily during pregnancy and for six months after childbirth is associated with lower levels of specific antibodies targeting the thyroid in women with autoimmune thyroiditis, compared to those taking a placebo.

67

0

85%

In women with autoimmune thyroiditis, levels of thyroid autoantibodies typically drop during pregnancy and rise again after childbirth unless selenium is taken, which may help prevent this increase.

67

0

80%

Taking selenium supplements does not change the levels of thyroid-stimulating hormone (TSH) in adults with chronic autoimmune thyroiditis, whether or not they are taking levothyroxine.

39

0

74%

Taking selenium supplements during pregnancy does not improve or worsen the mother's well-being, pregnancy complications, or baby's health outcomes in women with autoimmune thyroiditis.

67

0

73%

In adults with chronic autoimmune thyroiditis, taking selenium supplements may lead to changes in how the thyroid appears on ultrasound, but these changes do not result in better thyroid hormone levels or reduced symptoms.

39

0

71%