The Claim

Short-term (8-week) supplementation with Ashwagandha root extract at 600 mg/day is not associated with clinically significant changes in liver function markers (AST, ALT) in adults with stress and anxiety, as both groups maintained normal ranges throughout the study.

Source: Safety of 8-Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi-Center, Double-Blinded, Placebo-Controlled Study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
80score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Taking 600 mg of Ashwagandha root extract daily for 8 weeks does not significantly alter liver enzyme levels (AST and ALT) in adults with stress and anxiety. Both the supplement and placebo groups maintained normal liver function throughout the study.

See the scientific wording

Short-term (8-week) supplementation with Ashwagandha root extract (ARE) at 600 mg/day is not associated with clinically significant changes in liver function markers (AST, ALT) in adults with stress and anxiety, as both groups maintained normal ranges throughout the study.

Why this might work

The liver breaks down Ashwagandha root extract using its normal processes without creating harmful byproducts. The liver cells stay healthy, so the enzymes that show liver damage (AST and ALT) remain at normal levels.

Hypothetical mechanismbased on 1 study

What the research says

1 study

  1. Study: Safety of 8-Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi-Center, Double-Blinded, Placebo-Controlled Study.

    The study found that taking Ashwagandha root extract for 8 weeks did not harm the liver — liver enzyme levels stayed normal and were similar to people taking a placebo.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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