The Claim

Six weeks of supplementation with 10 grams of creatine monohydrate and 2 grams of guanidinoacetic acid significantly increases correct response rate by 9.1% in the Digit Vigilance test compared to supplementation with guanidinoacetic acid alone.

Source: Effects of 6 weeks of high-dose creatine monohydrate supplementation with or without guanidinoacetic acid on cognitive function

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
68score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Taking 10 grams of creatine monohydrate and 2 grams of guanidinoacetic acid daily for six weeks improves performance on the Digit Vigilance test by 9.1% compared to taking guanidinoacetic acid alone.

See the scientific wording

Six weeks of supplementation with 10 grams of creatine monohydrate and 2 grams of guanidinoacetic acid significantly increases correct response rate by 9.1% in the Digit Vigilance test compared to guanidinoacetic acid alone, indicating improved sustained attention and psychomotor accuracy.

Why this might work

Taking creatine and guanidinoacetic acid together raises the amount of high-energy fuel in brain cells. This fuel lets neurons quickly recharge their energy when they are firing rapidly during tasks that require constant focus. With more energy available, the brain processes information faster and makes fewer mistakes on tasks that demand prolonged attention.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of 6 weeks of high-dose creatine monohydrate supplementation with or without guanidinoacetic acid on cognitive function

    People who took both creatine and guanidinoacetic acid together made 9% fewer mistakes on a task that required staying focused for a long time, compared to those who took only guanidinoacetic acid. This means the combo helped them pay better attention.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.