Taking caffeine before high-intensity sprint workouts does not lead to greater improvements in blood fat levels—such as cholesterol and triglycerides—than doing the workouts without caffeine, in women who are overweight or obese.

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Pro

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Against

Evidence from Studies

Supporting (1)

54

Community contributions welcome

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Caffeine-augmented Sprint interval training outcomes in obese women: an examination by inter-individual analysis on physical and physiological adaptive responses

Randomized Controlled Trial

Human

2025

This study found that drinking caffeine before intense workouts didn’t make cholesterol or triglycerides any better in overweight women than just doing the workouts alone. So, caffeine helps with fat loss and fitness, but not with improving blood fats.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Caffeine-augmented Sprint interval training outcomes in obese women: an examination by inter-individual analysis on physical and physiological adaptive responses

Score: 54

DOI: 10.3389/fnut.2025.1655449

Similar Assertions

Taking caffeine before high-intensity interval workouts may lead to more consistent changes in body fat, muscle strength, heart fitness, blood sugar, and fat-related hormones among overweight and obese women.

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90%

In overweight and obese women, 12 weeks of sprint interval training reduces fat mass and improves strength, heart and lung fitness, and metabolic health. Adding caffeine to this training provides only minor extra benefits.

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54

86%

In sedentary overweight and obese women, taking a caffeine dose of 3 mg per kilogram of body weight 60 minutes before three weekly sprint training sessions for 12 weeks is associated with larger decreases in body fat, greater gains in leg strength, and improved aerobic fitness compared to taking a placebo.

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81%

In overweight and obese women, taking 3 mg/kg of caffeine before sprint interval training for 12 weeks leads to larger decreases in fasting blood glucose and more favorable changes in certain metabolic signaling proteins compared to taking a placebo during the same training program.

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80%

Taking caffeine while doing resistance training does not lead to meaningful changes in body fat or muscle mass over six weeks in active men, even though some muscles may appear thicker.

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77%