The Claim

Citrulline-malate ingestion is associated with a small but statistically significant increase in diastolic blood pressure during recovery from upper-body resistance exercise in trained males, with no change in systolic blood pressure.

Source: Effects of Supplemental Citrulline-Malate Ingestion on Blood Lactate, Cardiovascular Dynamics, and Resistance Exercise Performance in Trained Males

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
48score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In trained males, taking citrulline-malate after upper-body weight training is linked to a small but measurable rise in diastolic blood pressure during recovery, while systolic blood pressure does not change.

See the scientific wording

Citrulline-malate ingestion is associated with a small but statistically significant increase in diastolic blood pressure during recovery from upper-body resistance exercise in trained males, though systolic blood pressure remains unchanged.

Why this might work

Citrulline-malate is converted into arginine, which the body uses to make nitric oxide. Nitric oxide relaxes the walls of small blood vessels, making them wider. During recovery from upper-body exercise, this widening lowers resistance to blood flow, but because the heart is still pumping strongly from the workout, the pressure in the arteries when the heart is at rest (diastolic pressure) rises slightly. The pressure when the heart pumps (systolic pressure) stays the same because the heart's force doesn't increase.

Suggested mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of Supplemental Citrulline-Malate Ingestion on Blood Lactate, Cardiovascular Dynamics, and Resistance Exercise Performance in Trained Males

    In a study with trained men, taking citrulline-malate after upper-body workouts slightly increased the lower number in their blood pressure readings, but didn’t change the upper number — just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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