The Claim
Creatine supplementation for 12 months does not impair kidney or liver function in postmenopausal women, as indicated by stable creatinine clearance and no significant changes in liver enzyme levels compared to placebo.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking creatine supplements for 12 months does not cause changes in kidney or liver function tests in postmenopausal women compared to taking a placebo.
See the scientific wording
Creatine supplementation does not impair kidney or liver function in postmenopausal women over 12 months, as evidenced by normal creatinine clearance and no significant changes in liver enzymes compared to placebo.
Creatine is processed by the body into creatinine, which is filtered out by the kidneys without damaging them. The liver does not break down creatine in a way that produces harmful substances, so liver enzymes stay normal. Even with long-term use, the body handles creatine like a natural compound, and its waste product is cleared safely without overloading either organ.
What the research says
1 studyStudy: Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women.
This study gave older women creatine daily for a year while they did strength training and checked their kidney and liver health with standard blood and urine tests. No harm was found—everything stayed normal, just like in the group that took a sugar pill.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.