The Claim

Creatine monohydrate supplementation at doses up to 5 grams per day for up to 24 months does not increase serious adverse events, renal dysfunction, or clinically significant changes in liver or kidney biomarkers compared to placebo in postmenopausal women.

Source: Creatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
94score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

Taking up to 5 grams of creatine monohydrate daily for up to two years does not cause serious side effects, kidney damage, or abnormal liver or kidney blood test results in postmenopausal women compared to taking a placebo.

See the scientific wording

Creatine monohydrate supplementation at doses up to 5 grams per day for up to 24 months is safe and well-tolerated in postmenopausal women, with no increase in serious adverse events, renal dysfunction, or clinically significant changes in liver or kidney biomarkers compared to placebo.

Why this might work

Creatine is processed by the body into a harmless waste product called creatinine, which is filtered out by the kidneys without damaging them. The amount produced from taking up to 5 grams a day is small and stays within the body’s normal ability to handle it, so the kidneys and liver are not overloaded or harmed.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Creatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis

    This study found that postmenopausal women who took 5 grams of creatine daily for up to two years didn’t have more kidney problems or serious side effects than those who took a placebo — just mild stomach issues, if any. So, it’s safe for them to take it.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.